Large-scale biologics CDMO

therapiAI 協助某大型生物製劑 CDMO 導入 BioFusion Analytics AI Agent,以 AI 驅動細胞培養參數分析與產能預測模型,成功實現高穩定度的抗體藥物生產流程。

Client Challenge

This company focuses on API manufacturing.
Traditional process optimization relies heavily on expert experience and sequential testing, adjusting only a few parameters at a time.
This makes it difficult to evaluate multi-parameter interactions, resulting in long development cycles and inefficient use of resources.

The client needed a systematic approach to parameter selection and process optimization to reduce cycle time and dependence on experiential decision-making.

Solution Implemented

導入BioFusion Analytics AI Agent,透過 AI 進行細胞培養條件建模與產量預測,預測出具高抗體表現潛力的細胞株,協助研究團隊大幅縮減需實際培養與驗證的候選細胞數量,將篩選範圍精準聚焦於最具生產優勢的細胞株,顯著提升篩選效率與抗體產量。

Results Achieved

The AI models accurately identified high-productivity clones, reducing cultivation and validation workload while lowering material and labor costs.
Even with the same development timeline, overall production costs decreased by approximately 75%, greatly improving resource efficiency.

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Client Challenge This

By using AI to model cell culture conditions and predict yield, cell lines with high antibody performance potential can be identified, helping research teams significantly reduce the number of candidate cells that need to be actually cultured and validated.

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